超高效液相色谱-串联质谱法测定饮用水中6 种有机锡
张彩凤
(浙江捷岛检测科技有限公司,杭州 310030)
Determination of six organotins in drinking water by ultra performance liquid chromatography-tandem mass spectrometry
张彩凤
Zhejiang Jiedao detection technology Co., Ltd, Hangzhou 310030, China
摘要:建立饮用水中二苯基二氯化锡(DPT)、三苯基氯化锡(TPT)、二丁基二氯化锡(DBT)、三丁基氯化锡
(TBT)、三环锡(CYT)、三唑锡(AZT) 6 种有机锡的超高效液相色谱-串联质谱检测方法。采用直接进样,流动相A
为甲醇-0.1% 甲酸溶液,流动相B 为0.1% 甲酸-5 mmol/L 甲酸铵缓冲盐溶液,梯度洗脱,用多反应监测(MRM)模
式检测。6 种有机锡化合物的质量浓度在1.0~100.0 ng/mL 范围内与定量离子的丰度值线性关系良好,相关系数
为0.998~0.999,检出限为0.003~0.127 ng/mL。样品在2.0、10.0、50.0 ng/mL 3 个添加浓度水平时的平均回收率为
83.0%~121.4%,测定结果的相对标准偏差为0.00%~7.74%(n=6)。该方法满足水质中多种有机锡的检测要求。
Abstract:A method of determination of six organotin including dichlorodiphenyl-Stannane(DPT),
chlorotriphenyltin(TPT), dibutyltin dichloride(DBT), chlorotributyltin(TBT), cyhexatin(CYT) and azocyclotin(AZT) in
drinking water by ultra performance liquid chromatography-tandem mass spectrometric was established. Sampling direct
injection, the mobile phase A was methanol-0.1% formic acid solution, and the mobile phase B was 0.1% formic acid-5
mmol/L ammonium formate buffer solution. The gradient elution was used and the multi reaction monitoring mode(MRM)
was used for detection. The mass concentration of six organotins compounds had a good linear relationship with the
quantitative ion abundance values in the range of 1.0-100.0 ng/mL, the correlation coefficients were 0.998-0.999, and
the detection limits were 0.003-0.127 ng/mL. The average recoveries of the samples at 2.0, 10.0, 50.0 ng/mL levels was
83.0%-121.4%, and the relative standard deviations of determination results were 0.00%-7.74%(n=6). The method can
meet the requirements of determination of variety of organotin in water.
关键词:超高效液相色谱-串联质谱法;饮用水;有机锡
Keywords:ultra performance liquid chromatography-tandem mass spectrometry; drinking water; organotin
本文引用格式:
张彩凤. 超高效液相色谱- 串联质谱法测定饮用水中6 种有机锡[J]. 化学分析计量,2021,30(10):33.
Zhang Caifeng. Determination of six organotins in drinking water by ultra performance liquid chromatography-tandem mass spectrometry[J]. Chemical Analysis and Meterage,2021,30(10):33.
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